Neutrophil gelatinase-associated lipocalin (NGAL) predicts the occurrence of malaria-induced acute kidney injury

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Neutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.

BACKGROUND Neutrophil gelatinase-associated lipocalin (NGAL) is an early marker of acute kidney injury (AKI). METHODS AND RESULTS Urine NGAL and serum NGAL (sNGAL) were assessed at 2, 6, 24, and 48 hours after contrast media (CM) exposure in 458 high-risk patients (development set). Optimal thresholds in predicting contrast-induced AKI (serum creatinine [sCr] increase ≥0.3 mg/dL at 48 hours a...

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Neutrophil Gelatinase Associated Lipocalin (NGAL) in Leptospirosis Acute Kidney Injury: A Multicenter Study in Thailand.

AKI is one of the most serious complications of leptospirosis, an important zoonosis in the tropics. Recently, NGAL, one of the novel AKI biomarkers, is extensively studied in various specific settings such as sepsis, cardiac surgery, and radiocontrast nephropathy. In this multicenter study, we aimed to study the role of NGAL as an early marker and an outcome predictor of leptospirosis associat...

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Correction: Urine neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute canine kidney injury

After the publication of this work [1], we became aware of the fact that the values of NGAL reported in this study were concentrations of diluted clinic samples; and therefore for the actual concentration of urine NGAL, the value should multiply the dilution factor. With exception of Figure three (Figure 1 here), all the values of urine NGAL described in this study were detected by in-house ELI...

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Urinary Neutrophil Gelatinase–Associated Lipocalin (NGAL) Distinguishes Sustained From Transient Acute Kidney Injury After General Surgery

BACKGROUND This prospective study tests the hypothesis that after general surgery urinary NGAL can distinguish between sustained acute kidney injury (AKI), typical of nephron damage, from transient AKI, commonly seen with hemodynamic variation and prerenal azotemia. METHODS Urine was collected in 510 patients within 2-3 hr after general surgery and urinary NGAL was determined using ELISA. Pat...

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Urine neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute canine kidney injury

BACKGROUND Biomarkers for the early prediction of canine acute kidney injury (AKI) are clinically important. Recently, neutrophil gelatinase-associated lipocalin (NGAL) was found to be a sensitive biomarker for the prediction of human AKI at a very early stage and the development of AKI after surgery. However, NGAL has not yet been studied with respect to dog kidney diseases. The application of...

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ژورنال

عنوان ژورنال: Malaria Journal

سال: 2016

ISSN: 1475-2875

DOI: 10.1186/s12936-016-1516-y